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Updated: Jul 24, 2025

Interactome-Seq: A Protocol for Domainome Library Construction, Validation and Selection by Phage Display and Next Generation Sequencing
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Interactome-Seq: A Protocol for Domainome Library Construction, Validation and Selection by Phage Display and Next Generation Sequencing

Published on: October 3, 2018

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使用域到域翻译生成相互作用的蛋白序列.

Barthelemy Meynard-Piganeau1,2, Caterina Fabbri2, Martin Weigt1

  • 1Computational and Quantitative Biology, LCQB UMR 7238, Institut de Biologie Paris Seine, CNRS, Sorbonne Université, Paris 75005, France.

Bioinformatics (Oxford, England)
|July 3, 2023
PubMed
概括

这项研究引入了一种用于设计与特定合作伙伴相互作用的蛋白质序列的新方法,从而推进了蛋白质工程. 这种方法使用一个翻译框架来生成依赖于它们相互作用者的人工蛋白质域.

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