一个试验性随机临床试验的基地-在缓解镜镜治疗间歇性外热态的治疗
Allison I Summers, David G Morrison1, Danielle L Chandler2
1Vanderbilt University Medical Center, Nashville, Tennessee.
概括
这项试点研究发现,与非镜眼镜相比,基础镜眼镜无法改善间歇性外观的儿童的距离控制. 需要对这种条件下的镜适应进行进一步的研究.
科学领域:
- 眼科医生 眼科 眼科
- 儿科眼科医生 儿科眼科医生
- 眼的管理 管理 管理
背景情况:
- 间歇性外热症是一种常见的童年斜视.
- 底层镜眼镜是一种潜在的治疗策略.
- 间歇性外热症儿童的镜适应需要进一步研究.
研究的目的:
- 为了评估底层镜眼镜的疗效与仅针对儿童间歇性外观变异的折射校正.
- 确定是否需要进行全面的临床试验.
主要方法:
- 一项试点随机试验,涉及57名3至12岁的儿童,患有间歇性外热性.
- 参与者被随机分配,接受基内镜眼镜或非镜眼镜8周.
- 主要结果是远程控制得分的变化,预先定义了进行全面试验的标准.
主要成果:
- 在8周后, prism和非 prism组之间没有观察到远距离控制的显著差异.
- 调整后的差异有利于非镜眼镜,满足"不要继续"标准,进行全面的试验.
- 置信区间表明, prism 的临床显著有利效果不太可能.
结论:
- 底层镜眼镜在改善儿童间歇性外观变异的距离控制方面没有表现出比单独的折射校正更高的疗效.
- 该研究没有提供足够的证据来支持全面的随机试验.
- 定义和测量间歇性外热带儿童的镜适应的挑战需要进一步的研究.
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