在原始器官启动过程中,对auxin输出的遗传稳定性控制
Yuqiu Dai1, Linjie Luo2,3, Zhong Zhao1
1Chinese Academy of Sciences Center for Excellence in Molecular Plant Sciences, Ministry of Education Key Laboratory for Cellular Dynamics, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China.
概括
在植物器官启动中,通过调节DORNROSCHEN-LIKE (DRNL) 的MONOPTEROS (MP) 实现了遗传强度. DRNL抑制细胞因素,并补偿其对应物DRN,确保正常发育.
科学领域:
- 植物生物学 植物生物学
- 分子遗传学 分子遗传学
- 发育生物学是发展生物学.
背景情况:
- 辅酶信号传递对于植物器官启动至关重要.
- 在这个过程中控制辅酶输出的遗传强度机制尚不清楚.
研究的目的:
- 为了识别器官启动期间参与强大的辅酶信号传递的基因.
- 为了阐明控制器官创始细胞规范的监管网络.
主要方法:
- 酵母两杂交测试以确定蛋白质相互作用.
- 定量实时PCR (qRT-PCR) 用于分析基因表达.
- 在Arabidopsis thaliana中对突变表型的分析.
主要成果:
- 德诺诺申-莱克 (DRNL) 被确定为蒙诺普特罗斯 (MP) 的直接目标.
- MP与DRNL进行物理相互作用,通过激活关键基因来抑制细胞因素的积累.
- 类似的基因DORNROSCHEN (DRN) 补偿了drnl的功能丧失,证明了空间基因补偿.
结论:
- 建议在器官启动中提供强大的辅酶信号控制机制框架.
- 类似基因触发的空间基因补偿是强度的关键机制.
- 通过调节细胞因子水平,DRNL和DRN的相互作用确保了精确的器官启动.
相关概念视频
Combinatorial Gene Control
8.4K
Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
8.4K
Plant Hormones
24.3K
Plant hormones—or phytohormones—are chemical molecules that modulate one or more physiological processes of a plant. In animals, hormones are often produced in specific glands and circulated via the circulatory system. However, plants lack hormone-producing glands.
24.3K
Gene Regulation During Sporulation
36
Sporulation is a complex developmental process that allows certain Gram-positive bacteria, such as Bacillus subtilis and Clostridium species, to survive extreme environmental conditions. This process is tightly regulated by a series of signaling cascades and transcriptional controls, ensuring the formation of a highly resistant endospore.Sporulation is triggered by unfavorable conditions, such as nutrient depletion, and is governed by a phosphorelay system. One of the sensor kinases, such as...
36
Morphogenesis
28.5K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
28.5K
Cell Signaling in Plants
5.7K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
5.7K
Transgenic Plants
7.3K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
7.3K


