不同的有氧运动对老年轻度认知障碍患者的整体认知功能的影响:元分析
Conglin Han1,2, Weishuang Sun1,2, Dan Zhang1,2
1Beijing Rehabilitation Hospital, Capital Medical University, Beijing, China.
BMJ open
|July 3, 2023
概括
多元组件和心身有氧运动显著改善了轻度认知障碍 (MCI) 的老年人的认知功能. 心身运动在这个人群中显示出对认知健康的最可靠的益处.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 运动生理学 运动生理学
背景情况:
- 轻度认知障碍 (MCI) 影响着相当一部分老年人群.
- 全球认知功能下降是衰老和MCI的标志.
- 有氧运动越来越多地被研究其神经保护作用.
研究的目的:
- 系统地审查和元分析不同类型的有氧运动对MCI老年人的全球认知功能的影响.
- 确定最有效的运动方式,以提高MCI患者的认知能力.
主要方法:
- 进行了随机对照试验 (RCT) 的元分析.
- 通过对PubMed,EMBASE和Cochrane图书馆的全面搜索确定了研究,截至2022年3月.
- 认知功能是通过迷你心理状态检查 (MMSE) 和蒙特利尔认知评估 (MoCA) 进行评估的.
主要成果:
- 多组分有氧运动和心身运动在MCI患者的MMSE得分上显示出显著的好处.
- 心灵与身体,多元组件和传统的有氧运动都对MoCA分数产生了显著的积极影响.
- 灵敏度分析表明,传统有氧运动对MMSE得分的益处在统计学上并不显著,在一些分析中观察到很高的异质性.
结论:
- 多元组件和心身有氧运动对于改善MCI老年人的全球认知功能是有益的.
- 与多元组件和传统有氧运动相比,心身运动似乎提供了更可靠的认知改善.
- 可能需要进一步的研究来澄清MCI管理的最佳类型和强度的有氧运动.
更多相关视频
07:01Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
Published on: September 20, 2020
4.8K
10:19Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
Published on: August 22, 2014
14.3K
相关概念视频
01:30Cognitive Development During Adulthood
160
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
160
01:30Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
160
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
160
01:17Exercise and Cardiac Output
1.1K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
1.1K
01:22Alzheimer's Disease: Treatment
220
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
220
01:26Alzheimer's Disease: Overview
527
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
527
01:30Dementia
141
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
141