胆固醇消耗会降低非小细胞肺癌细胞对E-选择素的附着性

Amina Mohammadalipour1, Christian A Showalter2, Harrison T Muturi3

  • 1Department of Physics and Department of Biomedical Engineering, School of Science and Engineering, Saint Louis University, Saint Louis, Missouri, United States.

概括

在非小细胞肺癌 (NSCLC) 细胞中降低胆固醇会降低它们对E-selectin的附着性,这是转移的一个关键步骤. 在小细胞肺癌 (SCLC) 细胞中没有观察到这种效应,这表明有针对性的治疗方法.

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