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亚克西提尼布通过恢复线粒体功能来减轻肝纤维化的进展

Hailong Li1, Ruotong Zhang2, Yayue Hu2

  • 1The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.

International immunopharmacology
|July 3, 2023
PubMed
概括

亚克西提尼布通过改善肝脏健康和减少痕来治疗肝纤维化有望. 这种药物向线粒体功能,以抑制肝星细胞激活,提供一种潜在的新疗法.

关键词:
亚克西替尼布 (Axitinib) 是一种药物.肝脏纤维化 肝脏纤维化线粒体损伤导致线粒体损伤.在NLRP3炎症酶体中,NLRP3炎症氧化应激是一种氧化应激.

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