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一项对前列腺癌患者直肠体积变化的比较研究:一项第三级护理中心研究

P Umbarkar¹, V Kannan¹, V J Anand¹

¹Radiotherapy Section, Dept. of Medicine., PD Hinduja National Hospital and Medical Research Centre, Mumbai, 400016, India.

Radiography (London, England : 1995)

|July 3, 2023

概括

对于前列腺癌患者的早晨放射治疗,与下午治疗相比,直肠填充变化减少. 这种简单的时间调整可以提高辐射剂量的准确性.

科学领域:

辐射瘤学辐射瘤学
医学物理医学物理

背景情况:

在前列腺癌放射治疗期间直肠填充的变化可以显著影响预期的辐射剂量分配.
准确的剂量输送对于有效治疗和最大限度地减少副作用至关重要.

研究的目的:

调查一天中的治疗时间是否会影响前列腺癌放射治疗的患者的直肠填充.
为了确定早晨治疗是否导致与下午治疗相比更一致的直肠体积.

主要方法:

对50名局部性前列腺癌患者的回顾性分析,这些患者接受了体积调节弧线疗法 (VMAT) 治疗.
每日圆束计算机断层扫描 (CBCT) 扫描用于设置验证,直肠体积轮.
来自CBCT的直肠体积与计划CT扫描进行了比较,并计算了早晨 (AM) 和下午 (PM) 治疗之间的变化.

主要成果:

总共分析了50名患者 (AM和PM治疗) 的1000个CBCT图像集.
与计划CT相比,CBCT直肠体积的百分比变化在AM组为16.57%,在PM组为24.35%.
在AM组与PM组之间观察到直肠体积变化的统计学显著减少.

结论:

晨间放射治疗与下午治疗相比,直肠体积的变化明显较小.
将前列腺癌放射治疗转移到早上可能会提高输送辐射剂量分配的准确性.
一个简单的改变治疗时间到早上可以帮助最大限度地减少直肠体积变化在前列腺癌放射治疗.

关键词:

形光束计算机断层扫描前列腺癌是什么意思前列腺癌是什么意思放射治疗疗法放射治疗疗法结直肠体积是什么意思

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