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Updated: Jul 24, 2025

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作为药物发现工具的actin结合蛋白的冷EM结构

Christian Dahlstroem1, Themistoklis Paraschiakos1, Han Sun2

  • 1Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany.

Biochemical pharmacology
|July 3, 2023
PubMed
概括

动因动态是由动因结合蛋白 (ABP) 调节的. 通过使用 Cryo-EM 结构,针对 cofilin-1 和 L-plastin 与actin 的相互作用,可以提供新的癌症药物设计策略.

关键词:
在Actin中的Actin是Actin.癌症 癌症 癌症 癌症化电磁波是一种冷电磁波.细胞骨架 细胞骨架药物设计 药物设计转移 转移 转移 转移

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