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Updated: Jul 24, 2025

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
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Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

Published on: June 17, 2014

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化PTTG1切换其亚细胞分布,并促进β-catenin稳定和随后的转录活动

Xuewen Zhang1, Nianping Wu1, Huili Huang1

  • 1National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei Key Laboratory of Industrial Microbiology, Hubei University of Technology, Wuhan, China.

Oncogene
|July 3, 2023
PubMed
概括

下垂体瘤转化基因1 (PTTG1) 通过稳定β-catenin,激活Wnt/β-catenin信号传递来驱动肝细胞癌 (HCC). 这一发现为治疗HCC提供了潜在的新治疗点.

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