探索COVID-19的各种患者群体的通风治疗的临床益处,使用现实世界的数据
Mohsen Abbasi-Kangevari1, Ali Ghanbari1, Mohammad-Reza Malekpour1
1Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
透气疗法对COVID-19患者的益处不同,具体取决于年龄和并发症. 准则应优先考虑最有可能通过呼吸机支持恢复的患者,使用现实世界的数据进行有效的资源配置.
科学领域:
- 关键护理医学 关键护理医学
- 流行病学 流行病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 由于COVID-19大流行造成了呼吸机短缺,需要制定优先级指南.
- 确定哪些COVID-19患者从通风治疗中获益最多,对于资源分配至关重要.
- 现实世界的数据分析对于在公共卫生危机期间为临床决策提供信息至关重要.
研究的目的:
- 研究COVID-19住院患者的不同患者群体中通风治疗的临床益处.
- 根据患者人口统计和并发症,量化通风治疗对康复概率的影响.
- 为优化通风器分配策略提供基于证据的见解.
主要方法:
- 长度研究分析了599,340名住院成人COVID-19患者记录 (2020年2月 - 2021年6月).
- 使用了两个后勤回归模型:一个预测通风概率,第二个量化通风的临床益处.
- 分析将患者按年龄 (18-39岁,40-64岁,65岁以上),性别以及包括慢性呼吸道疾病 (CRD),恶性病,心血管疾病 (CVD) 和糖尿病 (DM) 在内的并发症分类.
主要成果:
- 10.0%的患者接受了通风,14.2%的患者死亡,85.8%的患者康复.
- 患有CRD和恶性瘤的40-64岁患者显示,通风的最大益处.
- 益处因年龄和并发症概况而异;患有CRD和CVD的老年患者受益最少.
结论:
- 通风治疗的好处高度针对患者,受年龄和潜在健康状况的影响.
- 确定优先级的指导方针应纳入现实世界的数据,以确保为恢复可能性最高的患者分配呼吸机.
- 基于证据的决策算法,考虑到干预的有用性,对于管理稀缺资源,如通风机至关重要.
更多相关视频
05:39Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
09:36Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
相关概念视频
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Mechanical Ventilation I: Indication and Settings
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
COPD: Management Using Bronchodilators and Corticosteroids
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
