用不同的内镜切除方法治疗食道颗粒细胞瘤的临床结果
Dae Gon Ryu1, Cheol Woong Choi2, Su Jin Kim1
1Department of Internal Medicine, Medical Research Institute, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Beomeo-ri Mulgeum-eup, Yangsan-si, 50612, Gyeongsangnam-do, Korea.
Scientific reports
|July 3, 2023
概括
修改的内镜粘膜切除 (EMR) 是安全有效的治疗食道颗粒细胞瘤 (GCTs). 这项研究发现,对于这些潜在的恶性瘤,各种EMR技术之间的结果没有显著差异.
科学领域:
- 胃肠病学和内镜检查
- 手术瘤学手术瘤学
- 胃肠道病理 胃肠道病理
背景情况:
- 食道颗粒细胞瘤 (GCTs) 是第二个最常见的食道亚皮质瘤 (SETs).
- GCT具有恶性潜力,但缺乏最终的管理指南.
- 内镜切除是食道GCTs的主要治疗方式.
研究的目的:
- 评估各种内镜切除方法对食道GCTs的临床结果.
- 评估修改内镜粘膜切除 (EMR) 技术的安全性和有效性.
- 为GCTs确定最佳的内镜管理策略.
主要方法:
- 对35名接受食道GCT内镜切除的患者的回顾性分析 (2008年12月 - 2021年10月).
- 使用了各种修改后的EMR技术,包括结辅助,常规,帽子辅助和水下EMR,以及内镜下膜剖析 (ESD).
- 评估临床和内镜结果,包括手术时间,切除率,并发症和复发率.
主要成果:
- 大多数GCT是无症状的,广泛的,白至黄色的,下,位于远端食道.
- 所有内镜手术均完成,平均手术时间为6.6分钟,没有并发症.
- 实现了100%的en-bloc和94.3%的完整组织切除率,在随访期间没有复发.
结论:
- 修改后的EMR方法证明了食道GCT切除的安全性和有效性.
- 在使用的不同内镜切除技术之间没有观察到临床结果的显著差异.
- 内镜切除是治疗食道GCT的可行和安全的选择.
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