人类的生存和选择的签名在化学传感基因上
Carrie C Veilleux1,2, Eva C Garrett3,4, Petar Pajic5
1Department of Anatomy, Midwestern University, 19555 N 59th Ave, Glendale, AZ, 85308, USA. cveill@midwestern.edu.
Communications biology
|July 3, 2023
概括
人类饮食的转变,就像农业一样,不会降低嗅觉 (OR) 和味觉 (TASR) 受体基因. 相反,生存行为推动了这些化学感知基因在不同种群中的本地适应.
科学领域:
- 人类进化生物学 人类进化生物学
- 遗传学 遗传学是一种遗传学.
- 感官科学是一种感官科学.
背景情况:
- 化学感知,包括嗅觉和味觉,对于食品的评估至关重要,并驱动化学感知基因的进化变化.
- 转向农业显著改变了人类的食物获取,一些研究表明,这导致了嗅觉退化.
研究的目的:
- 研究生存行为对嗅觉 (OR) 和味觉 (TASR) 受体基因的影响.
- 为了比较雨林采集者与非洲和东南亚的农民之间的化学传感基因进化.
主要方法:
- 对378个功能性OR和26个功能性TASR基因的分析.
- 研究包括133名来自乌干达 (Twa,Sua,BaKiga) 和菲律宾 (Agta,Mamanwa,Manobo) 的人口,具有不同的生存历史.
主要成果:
- 没有发现农业人口中化学传感基因放松选择的证据.
- 在每个地理区域内的化学传感基因中,发现了与生存相关的局部适应特征.
结论:
- 文化和经济因素,以及遗传漂移,在塑造人类化学感知知觉方面发挥着重要作用.
- 与之前的假设相反,农业似乎不会导致化学传感基因的广泛退化.
相关概念视频
Types of Selection
40.8K
Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...
40.8K
Frequency-dependent Selection
22.1K
When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
22.1K
What is Natural Selection?
115.7K
Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
115.7K
Natural Selection and Mating Preferences
136
The principle of natural selection posits that organisms better adapted to their environment are more likely to survive and reproduce. This principle is closely intertwined with mating preferences, a key aspect of sexual selection, which evolutionary psychologists believe is driven by instincts to propagate one's genes. Such instincts significantly influence mating behaviors and preferences between genders.
Females, due to their biological roles in conception, pregnancy, and nursing,...
Females, due to their biological roles in conception, pregnancy, and nursing,...
136
Background and Environment Affect Phenotype
6.6K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.6K


