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Updated: Jul 24, 2025

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
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在骨关节炎中ADAMTS12表达的表观遗传调节机制

Shu Yang1, Xuanping Zhou2, Zhen Jia1

  • 1Department of Orthopedics, Hunan Provincial People's Hospital (The First-affiliated Hospital of Hunan Normal University), No. 61, Jiefang West Road, Furong District, Changsha, Hunan, 410005, People's Republic of China.

Molecular medicine (Cambridge, Mass.)
|July 3, 2023
PubMed
概括

该METTL3 / IGF2BP2通路增强信号传感器和转录1 (STAT1) 的激活器的稳定性和表达,通过增加A解体和金属蛋白酶与血栓胺基因12 (ADAMTS12) 水平,促进骨关节炎 (OA). 沉默METTL3可以缓解OA的进展和软骨损伤.

关键词:
亚当斯12 亚当斯12 在在IGF2BP2BP2中使用.炎症 炎症是一种炎症.在METTL3中,METTL3是METTL3的第一个类型.骨关节炎是一种骨关节炎.美国国家统计局 (STAT1)

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