在Trichoderma reesei中,RGS4影响碳水化合物和 siderophore代谢
Miriam Schalamun1, Eva Maria Molin1, Monika Schmoll2,3
1AIT Austrian Institute of Technology GmbH, Bioresources Unit, Center for Health & Bioresources, Konrad Lorenz Strasse 24, Tulln, 3430, Austria.
BMC genomics
|July 3, 2023
概括
三甲虫reesei 在线阅读
科学领域:
- 菌类学 菌类学是指菌类学.
- 分子生物学分子生物学
- 生物化学 生化学
背景情况:
- 菌适应不断变化的环境依赖于信号通路.
- 异构三蛋白G蛋白通路对于真菌的适应至关重要.
- 在Trichoderma reesei中,G蛋白信号影响生长,酶生产和新陈代谢,通常以光线依赖的方式.
研究的目的:
- 研究Trichoderma reesei中的G蛋白信号传递 (RGS) 蛋白RGS4的SNX/H型调节器的功能.
- 确定RGS4在调节生理过程和基因表达中的作用.
- 阐明RGS4的特定功能,特别是对光和应激的反应.
主要方法:
- 在Trichoderma reesei中的RGS4蛋白的功能分析.
- 在各种条件下,RGS4删除突变体的表型特征.
- 转录组分析以确定RGS4调节基因.
- 生物现象型微阵列测试以评估特定营养来源的生长.
主要成果:
- RGS4调节细胞质的产生,生长,无性发育和应激反应 (氧化和透).
- 转录组分析显示,RGS4影响核糖体基因,与RutC30相关的基因,转录因子和转运体.
- RGS4积极调节 siderophore 集群用于沙林C生物合成,特别是在光线下.
- 与 siderophore 相关的营养物质和储存碳水化合物/银糖/氨糖通路的生长受到 RGS4 的影响,特别是在光线下.
结论:
- 在Trichoderma reesei中,RGS4主要在光线条件下运行.
- RGS4影响植物细胞壁降解, siderophore 生产和储存化合物代谢.
- RGS4是一个关键的调节器,将光信号与真菌的代谢和发育过程相结合.
关键词:
细胞质细胞质细胞质.这种植物名为Hypocrea jecorina.铁的平衡是铁的平衡.光响应对光的反应营养物质感应 营养物质感应它是G蛋白信号传递的调节器.这就是Siderophore.储存碳水化合物 的碳水化合物三甲虫reesei 在线阅读更多相关视频
07:21Author Spotlight: Unraveling the Interplay Between Trichoderma stromaticum and the Mammalian Immune System
Published on: October 20, 2023
1.4K
05:29Author Spotlight: Investigating Wolbachia-Induced Thelytokous Parthenogenesis and Genetic Toolkit Development Through RNA Interference
Published on: November 21, 2023
1.4K
相关概念视频
Riboswitches
8.2K
Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
8.2K
Global Regulatory Systems
44
Global regulatory systems in bacteria enable rapid and coordinated responses to environmental changes by integrating sensory inputs with gene expression, ensuring efficient adaptation to fluctuating conditions. Key global regulatory mechanisms include regulons, two-component systems, sigma factors, and secondary messengers.Regulons and Global RegulatorsA regulon is a collection of genes and operons controlled by a common global regulator. These regulators enable bacteria to prioritize resource...
44
Stringent Response in E. coli
31
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
31
Translational Regulation
45
Translational regulation in prokaryotes ensures efficient protein synthesis by controlling ribosome access to mRNA. This regulation is mediated by secondary RNA structures, including translational riboswitches, RNA thermometers, and small RNAs (sRNAs), which respond to intracellular and environmental signals to modulate gene expression.Translational RiboswitchesRiboswitches in the leader region of mRNAs can regulate translation by altering the accessibility of the Shine-Dalgarno (SD) sequence,...
45
