自闭症谱系障碍中的乳病:来自意大利儿童队列的数据
Stefania Zambrano1,2, Barbara Parma3, Valeria Morabito4,5
1Scientific Institute, IRCCS E. Medea Child Psychopathology Unit, Bosisio Parini, Lecco, Italy. s.zambrano.research@gmail.com.
Italian journal of pediatrics
|July 3, 2023
概括
这项研究发现自闭症谱系障碍 (ASD) 和腹腔疾病 (CD) 之间存在弱相关性. 定期的CD查不建议ASD患者比一般人群更多.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 神经发育障碍 神经发育障碍
- 免疫学 免疫学 免疫学
背景情况:
- 关于乳病 (CD) 和自闭症谱系障碍 (ASD) 之间的关联存在相互矛盾的研究.
- 一些研究表明CD在ASD病原发生过程中可能发挥作用,而另一些研究则没有证实这种联系.
研究的目的:
- 调查自闭症谱系障碍和腹腔疾病之间的潜在关联.
- 为了澄清儿科队列中CD和ASD之间的关系.
主要方法:
- 在2019-2020年间,对223名被诊断患有ASD的意大利儿童进行了前性研究.
- 对196名患者进行了乳清学查.
- 结核病的诊断遵循ESPGHAN的指导方针;费舍尔的精确测试比较了患病率与健康的意大利队列.
主要成果:
- 在ASD队列中,乳清性疾病的血清流行率为4.08%,相比之下,在健康组中为2.22% (p=0.0810).
- 在ASD队列中,明显的乳病患病率为2.24%,而在健康组中为1.58% (p=0.2862).
- 两者之间的差异都没有统计学意义,这表明相关性很弱.
结论:
- 这项研究证实了自闭症谱系障碍和腹腔疾病之间的弱相关性.
- 对于超出一般人群推的ASD患者,不建议进行常规的乳病查.
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