与标准的装配和填充茎相比,TiNbSn茎的扬氏模量和刚度的梯度变化降低了应力屏蔽
Kazuyoshi Baba1, Yu Mori2, Daisuke Chiba1
1Department of Orthopaedic Surgery, Tohoku University School of Medicine, 1-1 Seiryo-Machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.
European journal of medical research
|July 3, 2023
概括
与传统茎相比,TiNbSn (TNS) 茎在关节整形术 (THA) 后显著降低了应力屏蔽 (SS). 这种创新性的干显示出改善临床结果和减少并发症的前景.
科学领域:
- 整形外科手术 整形外科手术
- 生物材料科学 生物材料科学
- 医疗工程 医疗工程
背景情况:
- 应力屏蔽 (SS) 是由于骨和植入物茎之间的模块的差异而发生的.
- TiNbSn (TNS) 茎具有较低的扬氏模量和梯度的功能性质,可能减轻SS.
- 由Ti6Al4V合金制成的常规茎与显著的SS有关.
研究的目的:
- 评估TiNbSn (TNS) 干在全关节整形术 (THA) 后减少应力屏蔽 (SS) 的有效性.
- 为了比较TNS茎的临床结果与传统的Ti6Al4V合金茎.
主要方法:
- 一个前性临床试验比较TNS茎与Ti6Al4V合金茎 (对照组) 在初级THA.
- 茎与形状相匹配;在1岁和3岁时对SS和皮层缩 (CH) 的放射性评估.
- 临床结果使用日本整形医学协会 (JOA) 评分进行评估.
主要成果:
- 在TNS组中没有患者经历过3级或4级SS,而对照组在1年和3年分别有24%和40%.
- 与对照组相比,在TNS组中观察到明显较低的SS等级 (p < 0.001).
- 在TNS组中,JOA得分显著改善,并且在1年后与对照组相比较.
结论:
- 在THA后1年和3年,TNS茎有效地减少SS,相比于传统的近接结无茎.
- 使用TNS茎可能会导致减少茎松动和周围假肢骨折的情况.
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