环境变异的选择改变了肠道微生物组合,推动了动物的弹性
Cristina Casto-Rebollo1, María José Argente2, María Luz García2
1Institute for Animal Science and Technology, Universitat Politècnica de València, València, Spain.
Microbiome
|July 3, 2023
概括
减少子大小个体内变异的选择重新塑造了子肠道微生物组,增强了弹性. 这项研究将微生物组的转变与改善的肠道免疫力和动物的弹性联系起来.
科学领域:
- 动物遗传学和动物繁殖
- 微生物组研究的研究.
- 进化生物学是进化的生物学.
背景情况:
- 主体微生物组影响表型和对选择的反应.
- 选择适应性是可持续畜牧系统的关键.
- 个体内环境变异 (VE) 是动物弹性的一种代表.
研究的目的:
- 在子中确定肠道微生物组组成的基础VE的子大小 (LS).
- 研究如何选择低VE与高VE的LS影响肠道微生物组.
- 确定与子弹性相关的微生物和功能差异.
主要方法:
- 在两种子种群中,肠道微生物组的元基因组分析被分别选择为LS的VE.
- 部分最小正方形差异分析来区分种群.
- 阿尔法和β多样性分析以评估微生物组合.
主要成果:
- 确定了116个KEGG ID,164个COG ID和32种不同丰度的物种.
- 微生物组组成为VE种群实现了>80%的分类准确性.
- 低VE (弹性) 子显示出与肠道免疫相关的独特微生物特征和代谢途径.
结论:
- 选择VE的LS显著改变了子的肠道微生物组合.
- 微生物组的差异与肠道免疫调节和增强的弹性有关.
- 选择驱动的微生物群转变有助于复原性特征的遗传反应.
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