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Updated: Jul 24, 2025

Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons
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ER Ca2+ 过载激活了 IRE1α 信号,并促进了细胞生存

Song Zhao1,2, Haiping Feng1,2, Dongfang Jiang1,2

  • 1State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.

Cell & bioscience
|July 3, 2023
PubMed
概括

细胞内膜网膜 (ER) 的Ca2+过载直接激活IRE1α-XBP1通路,这是细胞信号传递的一个新发现. 这种激活对于预防TMCO1缺乏细胞中的细胞死亡至关重要.

关键词:
在 ER Ca2+ 超负荷的情况下.压力ERER压力ERER压力这就是IRE1α.在TMCO1中,

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