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在接受腹腔透析的儿科患者中,诱导的甲状腺功能低下症 (IIH):是否有可能降低风险?
Sai Sudha Mannemuddhu1,2, Heather A Morgans3,4, Bradley A Warady3,4
1Department of Pediatric Nephrology, East Tennessee Children's Hospital, Knoxville, USA.
概括
腹腔透析 (PD) 的儿童因暴露而面临甲状腺问题风险. 在PD治疗中提高意识和限制可以预防儿科患者的诱导的甲状腺功能低下症 (IIH).
科学领域:
- 儿科脏病学 儿科脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 患有功能衰竭,接受维持腹腔透析 (PD) 的儿童面临甲状腺功能障碍的风险增加.
- 由清洁溶液,对比剂或PD盖产生的过载是这些患者,特别是婴儿甲状腺功能低下症的未被认可的原因.
研究的目的:
- 调查有关PD患者暴露的国际做法.
- 为了确定在PD患者中诱导的甲状腺功能低下症 (IIH) 的发生率.
- 评估儿科病学家对PDIIH风险的认识.
主要方法:
- 一项国际调查分发给89个儿科脏病中心.
- 收集关于低甲状腺症诊断,怀疑IIH,暴露来源,甲状腺功能监测和暴露预防策略的数据.
主要成果:
- 在64%的中心诊断出甲状腺功能低下症; IIH疑似/诊断出只有33%.
- 主要的IIH原因:波维-PD盖 (53%),清洁溶液 (37%),有的对比度 (10%).
- 只有34%的中心限制暴露,81%的中心如果不积极监测/预防,就不会意识到IIH风险.
结论:
- 甲状腺功能低下症在全球儿科PD计划中很常见.
- 加强对暴露风险的教育至关重要,以减少患有PD的儿童的IIH发生率.
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