在抗氧化剂补充剂后,氧化还原和性能反应的个体间变化:一项随机双盲交叉研究
Nikos V Margaritelis1, George G Nastos1, Olga Vasileiadou1
1Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Serres, Greece.
Acta physiologica (Oxford, England)
|July 4, 2023
概括
抗氧化剂补充显示了运动表现和氧化应激标志物的各种个体反应. 个性化营养可能是优化运动员和活跃个体效益的关键.
科学领域:
- 运动生理学 运动生理学
- 营养生物化学 营养生物化学
- 人类表现的人类表现.
背景情况:
- 抗氧化剂缺乏会影响生理反应.
- 对补充剂反应的个体间变异性尚未得到充分理解.
研究的目的:
- 研究维生素C缺乏个体对抗氧化剂补充剂的氧化还原和生理反应的变异性.
- 为了比较低维生素C和对照组之间的反应.
主要方法:
- 根据血中维生素C水平,有200个个体被分为两层.
- 低维生素C组接受了30天的随机,双盲,交叉试验,使用维生素C或安慰剂.
- 评估了氧化应激标志物 (F2-异质) 和性能指标 (VO2max,同位数峰值扭矩).
主要成果:
- 与对照组相比,低维生素C组的氧化应激和性能受损较高.
- 补充剂显著改善了维生素C水平,减少了氧化应激,并提高了VO2max和同位数峰值扭矩.
- 观察到显著的个体间反应变化,超过了VO2max临床重要差异的最小值.
结论:
- 虽然大多数参与者从维生素C补充中受益,但部分人没有反应.
- 结果强调了在运动生理学中需要个性化的营养策略.
- 个体反应的变化强调了定制干预措施对于优化运动表现和健康的重要性.
更多相关视频
06:45Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K
Published on: January 11, 2019
9.2K
10:24Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
Published on: June 7, 2018
8.7K
相关概念视频
Redox Reactions
55.8K
Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...
55.8K
Redox Titration: Other Oxidizing and Reducing Agents
340
Besides iodine, other oxidizing or reducing agents can serve as titrants in redox titrations. Common oxidizing titrants include KMnO4, cerium(IV), and K2Cr2O7. The choice of oxidizing titrants depends on factors like stability, cost, analyte strength, and reaction rate between the analyte and titrant. KMnO4 is a strong oxidizing titrant that reduces from Mn(VII) to Mn(II) in a highly acidic solution, simultaneously oxidizing the analyte to a higher oxidation state. In this case, KMnO4 acts as a...
340
Oxidation of Phenols to Quinones
3.2K
In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
3.2K
Redox Equilibria: Overview
594
A reduction-oxidation reaction is commonly called a redox reaction. In a redox reaction, electrons are transferred from one species to another rather than being shared between or among atoms. The reducing agent or reductant is the species that loses electrons and gets oxidized in the process. The species that gains electrons and gets reduced in the process is the oxidizing agent or oxidant. Redox reactions are represented as two separate equations called half-reactions, where one equation...
594
Redox Titration: Overview
3.1K
Redox titration is a chemical analysis technique used to determine the concentration of an unknown substance by measuring the electron transfer in a redox (reduction-oxidation) reaction. The process involves gradually adding a titrant with a known concentration of an oxidizing or reducing agent, to the analyte, the solution with an unknown concentration, until reaching the endpoint, which indicates the completion of the reaction between the two substances. Ensuring the analyte is in a single...
3.1K
