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通过血管扩展剂诊断的心脏全移植血管病变心肌对比性回声心脏图像 perfusion 成像

Pooja Prasad¹, Raj Nagappan¹, Brian P Davidson¹

¹Oregon Health & Science University, Portland, OR, USA.

ESC heart failure

|July 4, 2023

概括

在心脏移植接受者的心脏全移植血管病变 (CAV) 监测可以利用血管扩展器应激心肌对比心声回声学 (MCE). 这种成像技术揭示了CAV的各种透模式,有助于早期检测.

科学领域:

心脏病学心脏病学
移植医学移植医学
诊断成像诊断成像诊断成像

背景情况:

心脏异体移植血管病变 (CAV) 是心脏移植后常见的长期并发症.
目前的黄金标准,侵袭性冠状动脉血管学,在检测早期或远端CAV方面存在局限性.
有限的数据存在于血管扩展应激心肌对比回声心脏图像输液成像 (MCE) 对于移植受体的CAV监测.

研究的目的:

评估血管扩张应激MCE在评估心脏移植接受者的微血管功能的实用性.
在CAV监测的背景下,描述MCE观察到的输液模式.

主要方法:

一系列的病例包括四名心脏移植接受者,他们正在接受CAV监测.
血管扩张应激MCE在休息状态下和经过雷加登诺森施用后进行.
连续输注脂外的微泡被用于 perfusion 成像.

主要成果:

MCE显示了各种微血管功能模式,包括正常功能,扩散功能障碍,斑点缺陷和焦点缺陷.
这些独特的输液模式在患有心脏全移植血管病变的患者中观察到.
侵袭性冠状动脉血管造影同时进行,以进行比较.

结论:

心脏全移植血管病变可以表现为心脏移植患者MCE上的多种 perfusion 模式.
在CAV.中,MCE显示了对微血管功能障碍的非侵入性评估的潜力.
需要进一步的研究来将这些MCE模式与预后和指导干预相关联.

关键词:

心脏异体移植血管病变心脏异体移植血管病变冠状动脉微血管功能障碍冠状动脉微血管功能障碍肌动脉对比回声心电图 (Myocardial contrast echocardiography) 是一种心肌肌动脉对比回声心电图.非侵入性诊断是一种非侵入性诊断.

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