系统性免疫炎症指数预测了下肢动脉样硬化治疗干预后的缩症 Obliterans
1Department of Intervention, Harrison International Peace Hospital, 053000 Hengshui, Hebei, China. jrktsy@outlook.com.
The heart surgery forum
|July 4, 2023
概括
治疗前的系统性免疫-炎症指数 (SII) 预测了下肢动脉样硬化 (ASO) 干预后的缩. 较高的SII水平与增加的复缩风险和较差的结果有关.
科学领域:
- 血管外科 血管外科
- 炎症生物标志物 炎症生物标志物
- 动脉样硬化 (ASO) 已经消失了
背景情况:
- 下肢动脉样硬化消灭症 (ASO) 影响着众多患者,静脉缩在干预后构成重大挑战.
- 识别可靠的复预测因子对于改善患者的治疗结果至关重要.
研究的目的:
- 为了研究治疗前系统性免疫炎症指数 (SII) 和下肢ASO内血管干预后的复原症之间的关联.
- 为了比较SII的预测值与其他炎症标志物对复原症的预测值.
主要方法:
- 对309名患有下肢ASO的患者进行了回顾性评估,这些患者接受了内血管干预.
- 预处理炎症标志物的收集和分析:SII,NLR,PLR,SIRI,AISI和CRP.
- 后勤回归和多变量分析,以确定与复原和临床结果的关联.
主要成果:
- 在治疗前的SII,NLR,PLR,SIRI,AISI和CRP在患有复缩症的患者中显著增加.
- 在预测缩 (0.715) 方面,SII显示了曲线下面面积 (AUC) 的最高值.
- 多变量分析确定预治疗SII是唯一的独立预测复原症 (HR:4.102,p=0.029).
- 较低的SII与改善的临床表现,ABI和生活质量有关.
结论:
- 治疗前SII是一种有价值和独立的预测器,可预测患有下肢ASO的患者的缩.
- 与其他评估的炎症标志物相比,SII在静止症的预后准确度更高.
- 使用SII可能有助于对ASO患者的风险分层和个性化治疗策略.
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