[男性患有与氧化应激相关的精子病症的不孕症治疗]
I V Vinogradov1,2,3,4,5,6,7,8, M Yu Gablia1,2,3,4,5,6,7,8, D S Rogozin1,2,3,4,5,6,7,8
1Department of Urology and Operative Nephrology with a course of oncourology, Peoples Friendship University of Russia, Moscow, Russia.
Urologiia (Moscow, Russia : 1999)
|July 4, 2023
概括
超级淋巴细胞通过减少氧化应激和改善精液参数来有效治疗男性不孕症. 这项研究显示精子度和形态的显著改善,提供了一个新的治疗选择.
科学领域:
- 生殖医学 生殖医学
- 生物化学 生物化学
背景情况:
- 氧化应激是男性不孕症的主要原因之一.
- 抗氧化剂治疗,包括调节性,对于管理男性不孕症中氧化应激至关重要.
- 超级淋巴,一个复杂的抗微生物和细胞因子,正在研究其治疗潜力.
研究的目的:
- 评估Superlymph在治疗与氧化压力相关的男性不孕症中的疗效.
- 评估Superlymph对精液参数和氧化应激标志物的影响.
主要方法:
- 一项前性多中心研究涉及30名男性不孕症患者,其反应性氧物种含量较高.
- 评估了标准精液分析,MAR测试,精子DNA损伤和活性氧物种水平.
- 患者每天接受Superlymph 25 IU,持续60天,并根据需要服用额外的抗生素或维生素D.
主要成果:
- 超级淋巴治疗显著增加了精子度和正常的精子形态.
- 在接受Superlymph的患者中观察到氧化应激水平的显著下降,无论是单疗法还是联合疗法.
- 虽然精子DNA碎片化减少,但差异没有达到统计学意义.
结论:
- 超级淋巴体对标准射精参数产生积极影响.
- 该治疗有助于减少精子DNA碎片化和男性不孕症患者的氧化应激水平.
- 超级淋巴体显示出作为治疗男性不孕症与氧化应激相关的治疗剂的承诺.
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