根据Promis计量表来估计中风中成本效益分析的公用事业
Nicolas R Thompson1, Brittany R Lapin1, Irene L Katzan2
1Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.
概括
这项研究比较了中风幸存者的健康实用措施,发现结果存在显著差异. 将PROMIS全球健康与HUI-3通过线性等式进行映射可能最适合中风患者.
科学领域:
- 卫生经济学 卫生经济学
- 神经学 神经学
- 研究结果研究成果.
背景情况:
- 建立了基于偏好的措施,如EQ-5D和HUI-3,对于成本效益分析至关重要.
- PROMIS偏好评分系统 (PROPr) 是一种基于偏好的新方法.
- 现有算法可以将PROMIS全球健康 (PROMIS-GH) 映射到HUI-3 (HUILE) 和EQ-5D (EQ5DLE).
研究的目的:
- 在成人中风幸存者中评估和比较PROPr和PROMIS-GH产生的健康效益.
- 评估不同实用措施的分布特征和与中风结果的相关性.
主要方法:
- 对4,159名成人中风幸存者的回顾性队列研究 (2015-2019).
- 对修改后的PROPr (mPROPr) 的计算.
- 与mPROPr,HUILE和EQ5DLE的中风结局的分布特征和相关性的比较.
主要成果:
- 平均效用估计有很大的差异:mPROPr (0.333),EQ5D (0.739),和HUI (0.544).
- 与修改的兰金尺度的相关性是mPROPr的 -0.48,EQ5DLE的 -0.43,HUILE的 -0.48.
- 回归分析表明mPROPr (对于健康患者来说太低) 和EQ5D (对于不健康患者来说太高) 的潜在偏差.
结论:
- 所有基于PROMIS的公用事业与中风严重程度相关,但呈现出不同的分布.
- 显著的差异凸显了成本效益研究评估健康状况的挑战.
- 通过线性等式 (HUILE) 将PROMIS-GH映射到HUI-3似乎最适合中风患者.
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