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在异形性内高血压中,光学通路的扩散张力MRI成像

Nada Elsaid¹, Ahmed Razek², Nihal M Batouty²

¹Department of Neurology, Faculty of Medicine, Mansoura University, Egypt.

The neuroradiology journal

|July 4, 2023

概括

扩散张力成像 (DTI) 显示,异常性内高血压 (IIH) 主要影响视神经 (ON),而不是光辐射 (OR). 在DTI指标与 papilledema 严重程度相关,有助于 IIH 诊断.

科学领域:

神经成像是一种神经成像.
眼科医生眼科眼科
神经学神经学

背景情况:

异形内高血压 (Idiopathic intracranial hypertension,IIH) 是一种原因不明的内压力升高的疾病.
光路干涉是IIH的标志,但具体受影响的部分需要进一步阐明.
扩散张力成像 (DTI) 提供了对白质微观结构完整性的洞察.

研究的目的:

评估DTI在评估IIH患者的视神经 (ON) 和视光辐射 (OR) 的实用性.
为了将DTI参数与IIH患者的乳头皮质的严重程度相关联.

主要方法:

一组41名IIH患者和22名健康对照人接受了DTI扫描.
分数异构性 (FA) 和平均扩散性 (MD) 为ON和OR计算,由两个独立的审查者进行.
DTI指标与 papilledema 的 funduscopic 级别相关.

主要成果:

在IIH患者和对照人群之间观察到ON FA和MD的显著差异 (p < 0.00001).
两组之间没有发现OR FA和MD的显著差异.
在FA和MD上,与乳头皮质等级有很强的相关性 (r = -0.8和0.951,分别).

结论:

IIH主要与前ON的变化有关,而不是后OR.
DTI衍生的ON的FA和MD作为IIH诊断的可靠成像生物标志物.
在DTI参数与 papilledema 严重程度的相关性很好,有助于疾病监测.

关键词:

扩散张力成像的成像方法异常发病的内高血压.视神经的视觉神经是如何工作的视觉路径的视觉路径

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