一般人群中精神病体验的发生率和持续性:系统性审查和元分析
Lorna Staines1, Colm Healy1, Felim Murphy1
1Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Schizophrenia bulletin
|July 4, 2023
概括
精神病经历 (PEs) 每年发生在2%的人口中,青少年的发病率最高. 在31%的病例中,这些PEs持续存在,在青春期也达到顶峰,并且与精神障碍有关.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 精神病经历 (PEs) 被认为是发展精神障碍的危险因素,特别是持久性PEs.
- 了解PES在一般人群中的发病率和持续性对于干预研究至关重要.
- 心理病可以作为精神健康状况的早期指标.
研究的目的:
- 系统地确定一般人口中精神病体验的发病率和持续率.
- 确定与PEs相关的人口因素,风险因素和结果.
主要方法:
- 在多个数据库 (Embase,Pubmed PMC,Psychinfo,Medline,Web of Science) 中进行了全面的双盲系统搜索.
- 使用NIH工具进行了数据提取和质量评估.
- 随机效应模型用于发生率和持续率的元分析,并对年龄和研究设计进行子组分析.
主要成果:
- 经皮质炎的综合发病率为0.023人/年 (每年每100人2人),青少年发病率最高 (100人5人).
- 预发性病的总持续率为31.0%,在青少年中也是最高的 (35.8%).
- 大麻使用与PEs的发病率有关,PEs与多种精神障碍有关.
结论:
- 每年,2%的普通人口经历新的精神病体验.
- 很大一部分 (31%) 患有PEs的个人经历了持久性,青少年是最脆弱的群体.
- 这些发现强调了监测PEs的重要性,特别是在青少年中,以及它们与心理健康结果和物质使用的关联.
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