血管内压力梯度和脑血流之间的相关性在症状,医疗耐药,前循环动脉狭窄的患者中:一项探索性研究
Long Li1, Bin Yang1, Adam A Dmytriw2,3
1Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, Beijing, China.
Journal of neurointerventional surgery
|July 4, 2023
概括
建立了对内动脉样狭窄症 (ICAS) 评估的新值. 压力梯度 (Pd/Pa=0.81,Pa-Pd=8 mm Hg) 与血液动力学不足相关,有助于ICAS管理决策.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 医疗成像医学成像
背景情况:
- 分流储备 (FFR) 是冠状动脉疾病的标准,其值为0.80.
- 内动脉样狭窄症 (ICAS) 的功能评估值仍然没有定义.
- 动脉旋转标签 (ASL) 为ICAS评估提供了输液参数.
研究的目的:
- 为了确定ICAS功能评估的潜在值.
- 为了将压力衍生的指数与ASL衍生的 perfusion 参数相对应.
- 在ICAS中建立可靠的血液动力学缺陷标记.
主要方法:
- 患有ICAS的患者接受了压力导线测量 (Pd/Pa,Pa-Pd) 和ASL成像.
- 在手术前和后测量脑血流 (CBF) 和相对CBF (rCBF).
- 由rCBF变化定义的可逆血液动力学不足 (<0.9至≥0.9).
主要成果:
- 分析了25名ICAS患者 (平均年龄为56.7岁).
- 已经确定了Pd/Pa=0.81和Pa-Pd=8mm Hg的值.
- 这些值与14名患者的可逆血动力学不足相关.
结论:
- 在ICAS中建立了转移性压力梯度的初步值.
- 0.81的Pd/Pa或8mm Hg的Pa-Pd可能表明血液动力学意义.
- 这些发现可以帮助ICAS管理的临床决策.
更多相关视频
05:23Author Spotlight: Noninvasive Cerebral Blood Flow Determination in Human Functional Brain Region for Diagnosis of Neurological Disorders
Published on: May 31, 2024
599
06:24Paired Cisterna Magna Nanoinjection and Laser Speckle Contrast Imaging Assay to Study Cerebral Blood Flow Regulation In Vivo
Published on: July 8, 2025
257
相关概念视频
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
17
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
17
Arteries of the Head and Neck
1.4K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
1.4K
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
13
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
13
