相关实验视频
Updated: Jul 24, 2025

07:17
An Orthotopic Resectional Mouse Model of Pancreatic Cancer
Published on: September 24, 2020
10.7K
[局部晚期胰腺癌转化疗法的进展和反思]
1Department of Pancreatic Surgery and Comprehensive Treatment,Fudan University Shanghai Cancer Center;Shanghai Pancreatic Cancer Institute;Pancreatic Cancer Institute, Fudan University,Shanghai 200032,China.
Zhonghua wai ke za zhi [Chinese journal of surgery]
|July 4, 2023
概括
转换手术为局部晚期胰腺癌 (LAPC) 患者提供了生存益处. 本综述总结了转换治疗的疗效指标,旨在提供由于缺乏标准化策略的临床指导.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 非手术治疗,解剖学分类和手术技术得到了改进,使局部晚期胰腺癌 (LAPC) 的转化手术成为可能.
- 越来越多的LAPC患者是转换手术的候选人,提供潜在的生存益处.
- 目前的临床实践缺乏LAPC转换治疗的标准化指南和定量标准,严重依赖外科医生的经验.
研究的目的:
- 总结对LAPC患者转换治疗的疗效评估指标.
- 思考各种转换治疗方式及其临床结果.
- 为临床实践提供基于证据的建议和指导.
主要方法:
- 对LAPC转换治疗的前性临床研究的文献综述.
- 综合关于治疗策略,疗效评估,手术时间和生存预后的数据.
- 分析现有证据,以确定治疗疗效的关键指标.
主要成果:
- 非手术和手术方法的重大进展扩大了LAPC转换手术的资格.
- 关于最佳转化治疗策略,疗效评估和预后因素的高级证据存在显著差距.
- 机构之间手术指示和治疗方案的变化凸显了对标准化标准的需求.
结论:
- 标准化疗效指标对于评估LAPC转换治疗至关重要.
- 需要进一步的研究,以建立基于证据的指导方针,在LAPC转换手术.
- 制定一致的建议将改善患者选择,并优化LAPC接受转换手术的结果.
相关概念视频
Treatment Resistant Cancers
3.3K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.3K
Chronic Pancreatitis II: Collaborative Care
115
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
115
Targeted Cancer Therapies
7.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.7K

