在非酒精性脂肪肝疾病中的生活方式干预
Zobair M Younossi1,2,3, Shira Zelber-Sagi4, Linda Henry5,6
1Betty and Guy Beatty Center for Integrated Research, Inova Health System, Falls Church, VA, USA. Zobair.Younossi@inova.org.
Nature reviews. Gastroenterology & hepatology
|July 4, 2023
概括
全球38%的成年人和10%的儿童患有非酒精性脂肪性肝病 (NAFLD). 改变生活方式,包括饮食和运动,至关重要,因为对于它的渐进形式,目前还没有药物治疗.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 非酒精性脂肪肝 (NAFLD) 是一种与代谢问题相关的慢性肝病.
- 全球患病率很高:成人38%,儿童10% (2016-2019年).
- NAFLD可以发展为非酒精性脂肪肝炎 (NASH),增加肝脏并发症,心血管疾病和癌症的死亡风险.
研究的目的:
- 突出NAFLD的重要性和缺乏药物治疗方法.
- 强调生活方式的改变作为NAFLD和NASH的主要干预措施.
- 倡导社区层面的变化,支持健康的环境.
主要方法:
- 文献综述和有关NAFLD流行病的流行病学数据的综合.
- 分析当前的治疗指南和限制.
- 讨论生活方式干预和公共卫生战略.
主要成果:
- NAFLD是一种广泛的慢性肝病,与代谢功能障碍有关.
- 目前还没有获得批准的药理疗法用于治疗NASH.
- 健康的生活方式选择是NAFLD管理的基石.
结论:
- 有效管理NAFLD取决于采用健康的生活方式,包括饮食和体育活动.
- 公共卫生倡议和政策变化对于创造有利于健康生活的环境至关重要.
- 需要涉及个人,社区和政策制定者的多方面的方法来打击NAFLD的流行率上升.
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