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Updated: Jul 24, 2025

Zebrafish Model of Neuroblastoma Metastasis
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PAX5-miR-142反循环通过调节 DNMT1 和 ZEB1 来促进乳腺癌的扩散

Zhao-Hui Chen1,2,3,4, Yi-Bo Chen1,2,3,4,5, Hao-Ran Yue1,2,3,4

  • 1The First Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Huan-Hu-Xi Road, He-Xi District, Tianjin, 300060, China.

Molecular medicine (Cambridge, Mass.)
|July 4, 2023
PubMed
概括

通过调节miR-142.5,PAX5在乳腺癌中起到瘤抑制作用. 这一途径涉及DNMT1和ZEB1的甲基化,形成一个反循环,影响癌症的进展,并提供新的治疗策略.

关键词:
乳腺癌是什么? 乳腺癌是什么在 DNMT1 中,DNMT1 是一个字符串.在PAX5中使用PAX5.核武器的扩散在ZEB1中,ZEB1是指ZEB1.在 miR-142-3p 中使用.在 miR-142-5p 中使用.

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