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Updated: Jul 24, 2025

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在第一个完整的人类基因组中,大规模基因组差异的表征

Xiangyu Yang1, Xuankai Wang1, Yawen Zou1

  • 1Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.

Genome biology
|July 4, 2023
PubMed
概括

新的端粒对端粒人类基因组组件 (T2T-CHM13) 显示了与GRCh38.38的显著结构差异. 这些基因组变异,特别是在复杂的区域,对于理解人类疾病和进化至关重要.

关键词:
完整的人类基因组 (T2T-CHM13)不一致的地区地区.人类参考基因组 (GRCh38)免疫系统疾病 免疫系统疾病在 KLRC 基因.大规模的结构变化.神经系统疾病 神经系统疾病

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