糖尿病足相关截肢的风险因素分析,包括控制营养状况得分和中性粒细胞与淋巴细胞的比率
Yandan Zhu1, Hongtao Xu2, Yuzhen Wang2
1Shanghai University of Traditional Chinese Medicine, Shanghai, China.
International wound journal
|July 5, 2023
概括
糖尿病足患者面临截肢风险. 关键预测因素包括的严重程度,部位,外围动脉疾病和免疫标记物,如中性粒细胞与淋巴细胞的比例和营养状况.
科学领域:
- 内分泌学 在内分泌学.
- 血管外科 血管外科
- 免疫学 免疫学 免疫学
背景情况:
- 糖尿病足经常导致截肢.
- 营养状况和免疫功能与糖尿病患者的截肢风险有关.
研究的目的:
- 确定糖尿病相关截肢的独立风险因素.
- 评估控制营养状况 (CONUT) 评分和截肢中性粒细胞与淋巴细胞比率 (NLR) 的预测值.
主要方法:
- 对389名糖尿病足患者的回顾性分析.
- 进行了单变量,多变量和卡普兰-梅尔分析.
- 评估了风险因素,包括的严重程度,部位,外围动脉疾病,CONUT得分和NLR.
主要成果:
- 确定了五个截肢的独立风险因素:的严重程度,部位,外周动脉疾病,NLR和CONUT得分.
- 观察到较低的无截肢存活率,中度至严重的,脚底前脚位置,外围动脉疾病的存在,以及高的NLR.
- 所有确定的因素都显示出对截肢进展的预测价值.
结论:
- 的严重程度,部位,外围动脉疾病,NLR和CONUT得分是糖尿病足患者截肢的重要独立风险因素.
- 这些因素可以预测糖尿病足的进展到截肢,有助于风险分层.
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