脂质概况和脂质蛋白 (a) 检测 测试
Klaus G Parhofer1, Ulrich Laufs
1Internal Medicine IV-Großhadern, LMU Hospital, Munich, Germany; Department of Cardiology, University Hospital of Leipzig, Leipzig, Germany.
Deutsches Arzteblatt international
|July 5, 2023
概括
准确的脂质状况评估对于预防心血管疾病至关重要. 通过改变生活方式和服用药物来降低LDL胆固醇是管理失脂症和降低健康风险的关键.
科学领域:
- 心脏病学 心脏病学
- 临床脂质学 临床脂质学
- 预防医学 预防医学
背景情况:
- 脱脂症严重影响心血管疾病 (CVD) 的初级和二级预防.
- 准确评估患者的脂质状况对于心血管疾病风险分层和指导治疗决策至关重要.
研究的目的:
- 审查当前的指导方针和文献,以有效管理失脂症.
- 为风险评估和治疗监测概述必要的脂质测量.
主要方法:
- 选择性文献搜索,包括当前的临床指南.
- 对脂质相关健康风险的诊断参数的审查.
主要成果:
- 关键的脂质测量包括胆固醇,甘油三,高密度胆固醇和低密度胆固醇,以及非高密度胆固醇.
- 脂蛋白 (a) 度测量有助于量化风险;它不能用口服药物治疗.
- 大多数脂质测试可以在非禁食状态下进行,除了过高甘油三血症的情况下.
结论:
- 胆固醇,甘油三,高密度胆固醇和低密度胆固醇的测量指导了降脂疗法.
- 脂质管理的主要目标是将LDL胆固醇水平降低到基于心血管风险的适当目标.
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