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Updated: Jul 24, 2025

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling
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DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling

Published on: October 8, 2019

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结合TSS-MPRA和敏感的TSS配置不相似度评分,研究转录启动的序列决定因素

Carlos Guzman1,2, Sascha Duttke1, Yixin Zhu1

  • 1Department of Medicine, Division of Endocrinology, U.C. San Diego School of Medicine, La Jolla, CA 92093, USA.

Nucleic acids research
|July 5, 2023
PubMed
概括

大规模并行报告员测试 (MPRA) 可以准确地捕获大约60%的发起者的转录开始地点 (TSS) 配置文件. 开发了一种新的TSS-MPRA协议和WIP评分方法,以评估MPRA对研究基因调节的忠实性.

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