在专科医院的患者中,非结核性真菌菌
Grazielle Conceição Sousa Barboza1, Isabela Neves de Almeida2, Lucas Benício Dos Santos1
1Universidade Federal de Minas Gerais, Faculdade de Medicina, Laboratório de Pesquisa em Micobactérias, Belo Horizonte, Minas Gerais, Brazil.
概括
这项研究详细介绍了巴西的非结核菌菌 (NTM) 疾病,发现 Mycobacterium kansasii 是主要的物种. 大多数患有NTM疾病的治疗患者经历了积极的结果,有很高的治愈率.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 非结核菌菌 (NTM) 疾病是一个诊断和治疗的挑战,特别是在像巴西这样的地区,关于发病率和临床特征的数据很少.
- 了解NTM感染的流行病学和临床表现对于有效的患者管理和公共卫生战略至关重要.
研究的目的:
- 在巴西东南部的一家三级医院调查NTM疾病的发病率,临床特征和治疗结果.
- 根据既定的指导方针确定占主导地位的NTM物种并评估治疗疗效.
主要方法:
- 从2008年1月至2019年7月期间从患者中分离的NTM的回顾性分析.
- 应用美国胸腔学会 (ATS) /美国传染病学会 (IDSA) 的诊断和治疗标准.
- 识别NTM物种,记录临床症状,评估治疗成功.
主要成果:
- 坎萨西菌 (Mycobacterium kansasii) 是最常被发现的NTM物种,占隔离物的11.5%.
- 超过一半的患者 (52.2%) 符合NTM疾病的ATS标准.
- 在接受治疗的患者中 (49.1%),观察到高75.8%的治愈率,呼吸障碍和咳是最常见的症状.
结论:
- 在这个巴西队列中,Mycobacterium kansasii是NTM疾病的重要原因.
- 目前的诊断和治疗指南似乎是有效的,导致大多数治疗患者的良好结果.
- 需要进一步的研究,以充分阐明巴西NTM疾病的负担和具体挑战.
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