维生素D与短期血压变化之间的关系
Amir Baniasad1, Abnoos Mokhtari Ardekan1, Mohammad Javad Najafzadeh2
1Department of Internal Medicine, Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences.
Blood pressure monitoring
|July 5, 2023
概括
新诊断高血压患者的维生素D缺乏与短期血压变化 (BPV) 的增加无关. 这项研究发现25-基维生素D (25(OH) D) 水平与BPV或门诊血压监测 (ABPM) 参数之间没有关联.
科学领域:
- 内分泌学 在内分泌学.
- 心血管医学 心血管医学
- 营养科学 营养科学
背景情况:
- 维生素D在心血管健康中起作用.
- 短期血压变化 (BPV) 是心血管风险的独立预测指标.
- 维生素D状况与高血压中的BPV之间的关系尚未得到充分证实.
研究的目的:
- 调查血清25-基维生素D (25(OH) D水平与短期血压变化 (BPV) 之间的关联.
- 评估新诊断的高血压患者在门诊血压监测 (ABPM) 中获得的25...OH) D水平和参数之间的关系.
主要方法:
- 招募了100名新诊断的第一阶段基本高血压患者.
- 患者被分为维生素D缺乏和不缺乏的群体,基于血清25...OH) D水平.
- 进行了24小时的门诊血压监测 (ABPM),以评估短期BPV.
主要成果:
- 血清25(OH) D水平和短期BPV或其他ABPM参数之间没有发现显著的关系.
- 血清,胆固醇和年龄与25...OH) D水平呈正相关性.
- 淋巴膜过率与25...OH) D水平呈负相关性.
结论:
- 在新诊断的高血压患者中,维生素D缺乏似乎不会通过影响短期BPV增加心血管风险.
- 虽然维生素D在心血管疾病中的作用是公认的,但在这种情况下,它对BPV的影响是可以忽略不计的.
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