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Updated: Jul 24, 2025

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眼睛表面疾病作为食道外胃食道逆流病的表现:一种特定的治疗策略

Antonio Di Zazzo1, Alessandra Micera2, Pier Luigi Surico1

  • 1Ophthalmology Complex Operative Unit, University Campus Bio-Medico, Rome, Italy.

Cornea
|July 5, 2023
PubMed
概括

胃食道逆流性疾病 (GERD) 和喉逆流 (LPR) 与增加的眼部不适有关. 局部阿尔金酸盐疗法在恢复眼睛表面健康和减少炎症方面表现有前途.

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Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
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Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
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Pharmacological management
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In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
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