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相关概念视频

Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

410
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
410
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

150
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
150
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

116
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
116
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

115
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
115
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

424
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
424
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

380
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
380

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相关实验视频

Updated: Jul 24, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
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急性胰腺炎的审查

Yuting Huang1, Dilhana S Badurdeen1

  • 1Department of Gastroenterology and Hepatology, Mayo Clinic, FL, USA.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
|July 5, 2023
PubMed
概括

急性胰腺炎的治疗已经进化,强调适度的液体复苏和早期的肠道养. 目前的指南和新的研究指南改善了患者护理,减少了并发症和死亡率.

科学领域:

  • 胃肠病学 胃肠病学
  • 临床医学 临床医学
  • 内部医学 内部医学

背景情况:

  • 急性胰腺炎的发病率每年增加约3%.
  • 由于最近的里程碑研究,2013年和2018年的现有指南需要更新.
  • 这种状况构成了具有潜在毁灭性后果的重大威胁.

研究的目的:

  • 审查目前的急性胰腺炎指南.
  • 提供临床实践改变文献的最新情况.
  • 为基于证据的临床决策提供信息,用于急性胰腺炎的管理.

主要方法:

  • 对当前急性胰腺炎指南进行系统审查.
  • 对最近的里程碑研究和改变临床实践的文献进行分析.
  • 包括来自WATERFALL等试验的发现和预期的GOULASH试验见解.

主要成果:

  • 建议使用乳酸林格溶液进行中度积极的液体复苏 (WATERFALL试验).
  • 不建议使用预防性抗生素;早期肠道养可降低发病率.
  • 建议个性化治疗疼痛,并考虑严重病例的外周止痛.

结论:

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Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
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相关实验视频

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Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
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  • 随着新的研究,急性胰腺炎的治疗有了显著的进化.
  • 早期的肠道营养和适当的液体复苏是减少发病率的关键.
  • 电解质,药理学剂,抗凝固剂和营养支持等正在进行的研究将进一步完善患者护理.