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肝炎C:一种罕见的亚急性的原因
Jennifer Ngo1, Robert Andalon1, Luis Delgado2
1Internal Medicine, University of California Riverside School of Medicine, Riverside, USA.
Cureus
|July 5, 2023
概括
型肝炎病毒 (HCV) 感染可能导致急性横侧髓炎 (TM),这是一种罕见的神经疾病. 早期HCV查对于患有TM等无法解释的神经缺陷的患者至关重要,以预防严重并发症.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 型肝炎病毒 (HCV) 主要通过血管炎和冷球蛋白血症影响周围神经系统.
- 最近的文献表明,慢性HCV感染和横向髓炎 (TM) 之间存在联系,但因果关系尚不清楚.
研究的目的:
- 报告一种罕见的急性横侧髓炎 (TM) 病例,该病例发生在新诊断为肝炎C病毒 (HCV) 感染的患者身上.
- 突出了急性神经缺陷和HCV之间的潜在关联.
- 强调在不明原因的TM病例中考虑HCV查的重要性.
主要方法:
- 一个31岁的男性患有急性双侧腿部软弱和尿液保留的病例报告.
- 诊断工作包括脊椎和大脑的MRI和腰部穿刺.
- 新确诊的C型肝炎病毒 (HCV) 感染与神经症状并发.
主要成果:
- 患者出现了急性双侧腿部软弱,在几天内进展,其次是尿液保留.
- 脊柱MRI揭示了胸髓内T2高强度信号,与横向骨髓炎 (TM) 一致.
- 大脑MRI和腰部穿刺的结果并不显著,排除了其他常见的原因.
结论:
- 这一案例表明急性横侧肌炎 (TM) 与新诊断的C型肝炎病毒 (HCV) 感染之间可能存在关联.
- 在出现不明原因的急性神经学缺陷,包括TM的患者中,应考虑对HCV进行查.
- 及时诊断和治疗HCV是减轻神经和全身并发症的必要条件.
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