剪切波弹性图:在慢性病中有用
Theertha Kuttancheri1, Kavitha Krishnan1, Sudha Kiran Das1
1Department of Radiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysore, India.
Polish journal of radiology
|July 5, 2023
概括
剪波弹性图 (SWE) 显示慢性病 (CKD) 患者的弹性降低. 年轻的年轻的年轻的年轻人年轻的年轻人
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 医疗成像医学成像
- 生物标志物 生物标志物
背景情况:
- 慢性病 (CKD) 是一个重要的全球健康问题.
- 内纤维化是CKD的常见途径,与疾病严重程度相关.
- 剪波弹性图 (SWE) 提供了组织刚性的非侵入性测量.
研究的目的:
- 评估从SWE获得的Young模块作为区分正常脏和患病脏的生物标志物.
- 将模量与多普勒发现和估计的淋巴细胞过率 (eGFR) 相对应.
主要方法:
- 展望性研究,初始阶段:50名CKD患者和50名对照人群,以确定中位Young的模量.
- 第二阶段:58名糖尿病患者和56名非糖尿病慢性病患者的横截面研究,使用SWE和多普勒.
- 在CKD阶段,对SWE发现与eGFR和多普勒参数的相关性分析.
主要成果:
- 皮层弹性,以扬模量来衡量,在CKD患者中与对照人群相比显著降低.
- 在模量,eGFR和抗性指数之间观察到显著的相关性.
- 在糖尿病和非糖尿病CKD组之间没有发现Young的模量有显著差异.
结论:
- 的模量与eGFR相关,这表明SWE在表明CKD中脏组织损伤方面的实用性.
- SWE可以帮助确定CKD的阶段,并提供补充的诊断信息,尽管它不能取代活检.
- 尽管SWE无法预测疾病病因,但它是CKD潜在的低成本诊断工具.
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