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Updated: Jul 24, 2025

Accessing the Cytotoxicity and Cell Response to Biomaterials

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

新酸水泥的生物相容性和矿化潜力

Byurira Kim¹, Yong-Hyuk Lee², Ik-Hwan Kim³

¹Department of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul, Republic of Korea.

Journal of dental sciences

|July 5, 2023

概括

新的酸水泥 (CSCs),NeoMTA Plus和EndoSequence根修复材料-快速设置 (ERRM-FS),显示与ProRoot MTA相比较的生物相容性和矿化潜力,使它们成为重要的脉治疗的合适替代品.

科学领域:

牙科材料科学牙科材料科学
生物材料工程生物材料工程
恢复性牙科恢复性牙科

背景情况:

酸水泥 (CSCs) 广泛用于重要的脉疗法.
许多新的CSC产品已经出现,需要对其性能进行评估.
ProRoot MTA 作为评估新型 CSC 的基准.

研究的目的:

评估两个新的CSCs的生物相容性和矿化潜力:NeoMTA Plus和EndoSequence根修复材料-快速集 (ERRM-FS).
将这些新材料与ProRoot MTA在体外和体内环境中进行比较.

主要方法:

在体外:评估每个CSC的干细胞活力,性酸酶 (ALP) 活性和离子释放.
在体内:使用ProRoot MTA,NeoMTA Plus或ERRM-FS对36颗牙进行了部分脉冲切除.
组织学分析评估了牙桥形成,脉炎症和治疗后的牙质层.

主要成果:

这三个CSC都在体外表现出类似的干细胞活力,ALP水平和释放.
与NeoMTA Plus相比,ProRoot MTA和ERRM-FS在体内表现出优异的组织愈合和质屏障质量.
在测试材料中,在新形成的状区域中没有观察到显著的差异.

结论:

NeoMTA Plus和ERRM-FS具有与ProRoot MTA相比的生物相容性和矿化潜力.
这些新型的CSC代表了临床应用的可行的替代方案,用于生命脉治疗.

关键词:

生物相容性生物相容性在酸水泥中,酸是最重要的.矿化潜力的矿化潜力部分脉冲切除术 (pulpotomy) 部分脉冲切除术

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