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多发性硬化症不安腿综合征:一个病例对照研究

Salman Aljarallah^1,2, Nuha Alkhawajah^1,2, Omar Aldosari¹

¹College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Frontiers in neurology

|July 5, 2023

概括

不安腿综合征 (RLS) 影响30.3%的多发性硬化症 (MS) 患者,显著增加疲劳和睡眠障碍的风险. 建议提高医生对MS中RLS的认识.

科学领域:

神经学神经学
睡眠医学睡眠医学
流行病学流行病学

背景情况:

不安腿综合征 (RLS) 是一种神经疾病,其特点是不可抗拒的动腿冲动.
多发性硬化症 (MS) 是中枢神经系统的一种慢性脱髓化疾病.
在MS (pwMS) 患者中RLS的患病率和影响需要进一步调查.

研究的目的:

为了确定pwMS中RLS的患病率.
为了检查RLS和MS疾病持续时间,睡眠障碍和白天疲劳之间的关联.
为了比较 pwMS 中的 RLS 患病率与健康的对照组.

主要方法:

一项涉及123名pwMS通过电话接受采访的横截面研究.
使用了经过验证的问卷:国际不安腿综合征研究小组 (IRLSSG) 标准,匹兹堡睡眠质量指数 (PSQI) 和疲劳严重程度量表 (FSS).
与健康对照队列相比,MS患者的RLS患病率.

主要成果:

在pwMS中,RLS患病率为30.3%,对照组为8.3%.
患有RLS的PwMS的疲劳风险增加了2.8倍,睡眠质量明显降低 (平均PSQI差异为0.64).
睡眠障碍和延迟是影响RLSpwMS睡眠质量的关键因素.

结论:

在患有多发性硬化症的患者中,RLS的发病率明显高于一般人群.
在MS中对RLS教育医疗保健提供者对于早期检测和管理至关重要.
在pwMS中解决RLS可能会改善疲劳和睡眠质量,提高患者的整体幸福感.

关键词:

疲劳疲劳疲劳疲劳疲劳疲劳多发性硬化症多发性硬化症患病率的流行情况.在多发性硬化症中出现不安腿综合征 (RLS).睡眠障碍睡眠障碍睡眠障碍

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