在脏恶性缩后早期对比度增强:成像发现与良性相关
Téodor Grand1,2, Christophe Delavaud3, Charles Dariane4,5
1AP-HP, Hôpital Necker Enfants Malades, Service d'Imagerie Adulte, F-75015, Paris, France. teodor.grand@aphp.fr.
European radiology
|July 5, 2023
概括
在结缩后的早期MRI对比增强通常是良性的. 在48小时MRI扫描中,冲洗指数低于-1.1准确预测脏恶性瘤的残留瘤 (RT).
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 对于脏瘤的早期MRI冷后的对比度增强可以模仿残留瘤 (RT).
- 在48小时内观察到的MRI增强可能会在6周内消失,表明良性变化.
研究的目的:
- 为了确定48小时的冷后MRI对比度增强的特征,从而预测剩余瘤的缺失.
- 评估washout指数的诊断性能,以区分良性增强与残留瘤.
主要方法:
- 对60名接受结缩 (2013-2020年) 的患者的回顾性分析,可用48小时和6周的MRI扫描.
- 评估了48小时的对比度增强 (CE);6周的持续/增长CE定义为RT.
- 冲洗指数是从48小时MRI计算的,使用ROC分析来评估RT预测.
主要成果:
- 83个冷凝区显示了48小时的增强;75个是良性的,8个有RT.
- 48小时的增强一直是动脉阶段.
- 洗与RT显著相关 (p<0.001),同时增加增强建议的良性 (p<0.009).
- 冲洗指数 < -1.1 预测RT,灵敏度为88%,特异性为84%.
结论:
- 在结缩后的早期MRI对比增强通常是良性的.
- 在48小时的MRI上,洗是残留瘤的关键指标.
- 冲洗指数 < -1.1 是残留瘤的可靠预测指标,有助于决定重复冷.
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