疾病活动指数与儿童的睡眠障碍之间的关系 炎症性肠道疾病的儿童
Dilsat Gundogdu1, Nafiye Urgancı2, Merve Usta3
1Pediatrics, SBU Sisli Hamidiye Etfal Training and Research Hospital, MD, Istanbul, Turkey.
European journal of pediatrics
|July 5, 2023
概括
患有炎症性肠病 (IBD) 的儿科患者经历了显著的睡眠障碍,与疾病活动密切相关. 匹兹堡睡眠质量指数 (PSQI) 和疾病活动指数有效预测这些儿童的睡眠障碍.
科学领域:
- 胃肠病学 胃肠病学
- 儿科 儿科 儿科
- 睡眠医学 睡眠医学
背景情况:
- 睡眠障碍是被诊断患有炎症性肠病 (IBD) 的儿科患者的常见投诉,即使在临床缓解期间也会持续存在.
- 匹兹堡睡眠质量指数 (PSQI) 是一种有效的工具,用于评估不同患者群体的主观睡眠质量.
研究的目的:
- 为了确定儿科IBD患者睡眠障碍的患病率.
- 研究IBD临床特征,疾病活性,炎症标志物和睡眠质量之间的关联.
- 评估疾病活动指数对儿科IBD睡眠障碍的预测价值.
主要方法:
- 对99名儿科IBD患者 (44名克罗恩氏病,55名性结肠炎) 和80名健康对照者的临床和人口统计数据,实验室参数和疾病活性进行了回顾性分析.
- 对所有参与者进行匹兹堡睡眠质量指数 (PSQI) 的管理.
- PSQI得分与临床/实验室参数之间的相关性分析,包括疾病活动指数 (儿科克朗氏病活动指数和儿科性结肠炎活动指数).
主要成果:
- 与健康对照组相比,儿科IBD患者的PSQI得分明显更高,表明睡眠质量较差.
- 患有IBD的患者,特别是患有性结肠炎的患者,报告睡眠时间较晚,睡眠时间较短.
- 在克罗恩氏病和性结肠炎患者的疾病活动指数,腹痛和PSQI得分之间观察到强烈的正相关性.
- 儿科克朗氏病活动指数和儿科性结肠炎活动指数被确定为睡眠障碍的独立风险因素,显示出高灵敏度和特异性.
结论:
- 在儿科IBD中增加的疾病活性显著损害睡眠质量.
- PSQI和特定儿科疾病活动指数 (PCDAI,PUCAI) 是识别和预测儿科IBD患者睡眠障碍的强有力的工具.
- 这些发现强调了评估睡眠质量的重要性,以全面管理儿科IBD.
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