Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

154
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
154
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

64
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
64
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

54
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
54

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Amidoxime-Based Near-Infrared Fluorescent Sensor for Highly Sensitive Uranium Detection in Living Systems.

Analytical chemistry·2026
Same author

The dual correlations between core beliefs changes and emotion regulation among disaster-affected residents: the moderating role of religiousness orientation.

Frontiers in psychology·2026
Same author

Microbial Degradation of Herbicide Residues in Australian Soil: An Overview of Mechanistic Insights and Recent Advancements.

Toxics·2025
Same author

Thermoelectric property regulation of dimer-triangulene molecular junctions based on oxygen edge-modification engineering.

Physical chemistry chemical physics : PCCP·2025
Same author

Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer.

Cell·2025
Same author

Enhancing carbonation resistance of alkali-activated fly ash-slag pastes: Role of albite and dolomite additives.

Environmental research·2025

相关实验视频

Updated: Jul 24, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.3K

基于多源特征和深度学习,预测潜在的微生物疾病关联.

Liugen Wang1, Yan Wang2, Chenxu Xuan2

  • 1School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, Jiangsu 214122, China.

Briefings in bioinformatics
|July 5, 2023
PubMed
概括
此摘要是机器生成的。

这项研究介绍了DSAE_RF,一种计算模型,可以有效地预测微生物与疾病的关联. 它利用深度学习来减少识别与疾病相关的微生物的时间和成本,帮助临床研究.

关键词:
k-表示集群的平均值.深度稀疏自编码神经网络的神经网络微生物与疾病的关联随机的森林随机的森林

更多相关视频

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

1.1K
A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

1.7K

相关实验视频

Last Updated: Jul 24, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.3K
Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

1.1K
A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

1.7K

科学领域:

  • 微生物学 微生物学
  • 计算生物学 计算生物学
  • 生物信息学是一种生物信息学.

背景情况:

  • 复杂的疾病与微生物群落有关,影响瘤发生和转移.
  • 临床观察疾病中的微生物群存在重大差距.
  • 目前用于识别与疾病相关的微生物的生物实验是准确的,但耗时且昂贵.

研究的目的:

  • 开发一种计算模型,有效预测微生物与疾病的关联.
  • 为了降低与识别与疾病相关的微生物相关的资本和时间成本.
  • 解决微生物群研究中传统实验方法的局限性.

主要方法:

  • 开发了一个新型模型,DSAE_RF,它结合了多源功能和深度学习.
  • 计算了微生物和疾病之间的四个相似之处,以创建特征向量.
  • 采用k-means集群用于可靠的负样本选,以及用于特征提取的深度稀疏自编码器.
  • 利用随机森林分类器来预测微生物与疾病的关联.

主要成果:

  • DSAE_RF模型实现了高性能,其AUC为0.9448和AUPR为0.9431.
  • 经过10倍交叉验证的广泛验证证明了模型的可靠性.
  • 包括负样本选择方法,模型比较和案例研究 (Covid-19,结直肠癌) 在内的比较分析证实了该模型的有效性.

结论:

  • DSAE_RF模型提供了一种可靠和高效的计算方法,用于预测微生物与疾病的关联.
  • 这种方法大大降低了识别与疾病相关的微生物所需的成本和时间.
  • 这些发现支持计算模型在推进临床微生物群研究和疾病理解方面的潜力.