在厄瓜多尔出现了第一批被测序的Omicron BA.2亚系病例
D A Andrade-Molina1, G A Morey-León2, K E Muñoz-Mawyin1
1Omics Sciences Laboratory, Faculty of Health Sciences, Universidad Espíritu Santo, Samborondón, Ecuador.
Virus research
|July 5, 2023
概括
SARS-CoV-2的BA.2变种在2022年3月在厄瓜多尔出现,是在Omicron波之后. 这项研究详细介绍了该国新型COVID-19变种的前五个被测序的病例.
科学领域:
- 病毒学 病毒学
- 流行病学 流行病学
- 基因组监测 基因组监测
背景情况:
- 厄瓜多尔在2021年底-2022年初经历了一次由Omicron (B.1.1.529/BA) 变种驱动的SARS-CoV-2 (COVID-19) 波.
- 在2022年3月,每日COVID-19病例的增加被记录在2022年3月,与新变种的出现相吻合.
研究的目的:
- 描述厄瓜多尔SARS-CoV-2 BA.2变种的出现和初始表征.
- 报告在该国发现的BA.2变种的第一个测序病例.
主要方法:
- 使用定量聚合酶链反应 (qPCR) 进行变异特异性基因型鉴定.
- 通过全基因组测序 (WGS) 确认已确定的病例.
主要成果:
- 在厄瓜多尔确定了第一批5例SARS-CoV-2变种21L/BA.2的测序病例.
- 一个病例最近有国际旅行史,而另外四个病例没有.
- 第一个被测序的BA.2分离物来自于一个在国际旅行后不久出现症状的个体.
结论:
- 到2022年3月,BA.2变种已经在厄瓜多尔传播.
- 包括qPCR和WGS在内的基因组监测对于跟踪新SARS-CoV-2变种的出现至关重要.
- 这些发现凸显了持续监测该国病毒演变和传播的必要性.
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