间歇性葡萄糖监测在幼犬中具有可接受的临床准确性
Zsofia Vigh1, Paula A Johnson1, Hsin-Yi Weng2
11Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN.
概括
间歇性葡萄糖监测器 (IGM) 是一种临床上可接受的工具,用于监测患病幼犬的血糖. 性能与兽医ICU中的便携式血糖监测器 (PBGM) 相当.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 进行比较诊断.
- 动物生理学 动物生理学
背景情况:
- 精确的葡萄糖监测对于管理生病的动物至关重要.
- 间歇性血糖监测器 (IGM) 为传统的便携式血糖监测器 (PBGM) 提供了潜在的替代方案.
- 关于在兽医重症监护室 (ICU) 设置中的幼犬IGM表现的数据有限.
研究的目的:
- 与便携式血糖监测器 (PBGM) 相比,评估间歇性葡萄糖监测器 (IGM) 的性能.
- 评估IGM读数与PBGM在患病幼犬中的临床准确性和一致性.
主要方法:
- 从16只幼犬中收集了配对间歇性和血糖样本.
- 使用皮尔森相关性,平均绝对相对差异 (MARD),偏差和95%的协议极限来确定分析准确性.
- 临床准确性通过帕克斯共识错误网格分析进行评估.
主要成果:
- 在IGM和PBGM测量之间观察到正相关性 (Pearson r = 0.65).
- 平均绝对相对差异 (MARD) 为15.4%,偏差为-2.6%.
- 100%的配对测量在共识错误网格上属于临床上可接受的区域 (A或B).
结论:
- 与幼犬的便携式血糖监测相比,间歇性血糖监测显示出临床上可接受的性能.
- 在临床兽医环境中,IGM可用于对患病的幼犬进行葡萄糖监测.
- 建议对更大的样本大小进行进一步的研究,特别是在低血糖范围,以充分评估IGM的性能.
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