益生菌性质和抗微生物评价与西利马林丰富的乳酸菌细菌从传统的奶酪中分离出来
Babak Haghshenas1, Amir Kiani2, Saeideh Mansoori3
1Regenerative Medicine Research Center (RMRC), Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Scientific reports
|July 5, 2023
概括
研究人员探索了含有西利马林的乳酸菌细菌的益生菌潜力和抗菌活性. 西利马林和益生菌的组合表明对抗阿斯伯吉卢斯黄菌的抗真菌作用得到了增强.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 药用植物越来越多地用于疾病治疗和预防.
- 乳酸菌细菌以其益生菌性质而闻名.
- 在食品和健康行业中,Aspergillus flavus存在风险.
研究的目的:
- 为了研究含有西利马林的乳酸菌细菌的益生菌特性.
- 评估这些菌株的抗菌和抗真菌活性.
- 评估西利马林和益生菌对病原细菌和Aspergillus flavus的联合作用.
主要方法:
- 从传统的乳酪样本中分离出52种格拉姆阳性,酶阴性细菌.
- 根据在酸性和胆盐条件下的高生存能力,选择了五种菌株.
- 益生菌性质的评估:疏水性,自聚,协聚和胆固醇去除.
- 对12种致病细菌和Aspergillus flavus的抗菌和抗真菌活性进行评估.
- 对西利马林和益生菌菌株的协同作用的分析.
主要成果:
- 五个选定的细菌菌株表现出显著的益生菌潜力.
- 所有测试的菌株都显示出抗菌和抗真菌活性.
- 西利马林和益生菌菌株的组合显著增强了对阿斯伯吉卢斯黄菌的抗真菌活性 (P < 0.05).
- 特定的菌株 (Limosilactobacillus fermentum C3,C18,和Lactiplantibacillus pentosus C20) 显示出明显的抑制阿斯伯吉勒斯黄在与西利马林结合时.
- DMSO和PEG溶剂中的西利马林放大了所有五种益生菌菌株的对抗活性.
结论:
- 富含西利马林的乳杆菌菌株具有有前途的益生菌和抗菌特性.
- 西利马林和益生菌的协同作用为对抗Aspergillus flavus提供了一个强有力的策略.
- 这些发现支持这些增强型益生菌在食品和卫生领域的潜在应用.
相关概念视频
01:28Biological Methods for Microbial Control
109
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
109
01:29Microorganisms in Medicine and Therapeutics
64
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
64
01:27Microorganisms in Agriculture and Food industry
93
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
93