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Updated: Jul 24, 2025

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治疗诱导的APOBEC3A驱动着持久性癌细胞的演变

Hideko Isozaki1,2, Ramin Sakhtemani3,4, Ammal Abbasi3

  • 1Massachusetts General Hospital Cancer Center, Boston, MA, USA. hisozaki@mgh.harvard.edu.

Nature
|July 5, 2023
PubMed
概括

向性肺癌治疗可以诱导APOBEC3A (A3A),导致持久性癌细胞的突变. 抑制A3A可能会延迟获得的耐药性,提供新的治疗策略.

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