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在巴西一家兽医医院环境中出现了抗微生物药物耐药的金黄色葡萄球菌
Denny Parente de Sá Barreto Maia Leite1,2, Iago Carvalho Barbosa1,2, Renato Amorim da Silva1,2
1Department of Veterinary Medicine, Federal Rural University of Pernambuco (UFRPE), Recife, Pernambuco, Brazil.
概括
兽医医院的抗菌素耐药性是一个公共卫生问题. 研究发现Staphylococcus aureus在工作人员,动物和表面中发现,强调需要进行感染控制以防止物种间传播.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 抗菌素耐药性 (AMR) 对全球公共卫生构成重大威胁.
- 抗生素耐药性黄金葡萄球菌菌株的出现需要紧急的预防策略.
研究的目的:
- 在兽医医院内从人类,动物和环境中隔离金黄色葡萄球菌.
- 描述孤立的S. aureus菌株的基因型和表型抗微生物耐药性概况.
主要方法:
- 从兽医人员,伴侣动物和医院表面采集的样本使用无菌抹布.
- 通过曼尼托盐,格拉姆染色和酶测试,分离和初步识别S. aureus.
- 使用聚合酶链反应 (PCR) 来确定物种确认和基因型耐药性概况,通过盘扩散试验确定表型耐药性.
主要成果:
- 黄金葡萄球菌从25%的人类,15.38%动物 (狗和猫) 和7.14%表面中分离出来.
- 在一只猫身上发现了对牛素敏感的MECA阳性黄金色杆菌S. aureus表型.
- 大多数分离物体含有多个耐药基因 (例如, blaZ, norA, ermB),对青素 (100%) 和红素 (80%) 观察到高耐药性.
结论:
- 在兽医环境中存在抗微生物药物耐药性黄金菌的存在强调了跨物种传播的风险.
- 细菌殖民动物和人类之间的基因转移可能会使抗微生物治疗复杂化.
- 在兽医医院加强监测和感染控制措施至关重要,以减轻AMR的传播.
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